Collection: PCR

A thermal cycler, also known as a PCR machine, is a laboratory device used to amplify segments of DNA through the polymerase chain reaction (PCR). It works by cycling through a series of precise temperature changes that facilitate the denaturation of DNA, annealing of primers, and extension of new DNA strands by a DNA polymerase enzyme. These repeated cycles allow for the exponential amplification of specific DNA sequences, making the thermal cycler an essential tool in molecular biology, genetics, medical diagnostics, and forensic science.